Molecular Oncology Almanac
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Therapeutic Response

v::ROS1 status confers therapeutic sensitivity to Entrectinib in patients with Non-Small Cell Lung Cancer.

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Statements

Source and description
Rozlytrek (entrectinib) [product monograph]. HC.

Health Canada approved entrectinib for the treatment of patients with ROS1-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) not previously treated with crizotinib.
Rozlytrek (entrectinib) [package insert]. FDA.

The U.S. Food and Drug Administration granted approval to entrectinib for the treatment of adult patients with ROS1-positive metastatic non-small cell lung cancer (NSCLC), as detected by an FDA-approved test.

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