Therapeutic Response Statement (Sensitivity)

This therapeutic response statement supports the relationship that v::ROS1 status confers therapeutic sensitivity to Crizotinib in patients with Non-Small Cell Lung Cancer.

This statement is based on a regulatory approval from the Health Canada:

XALKORI (crizotinib) is indicated for use in patients with ROS1-positive locally advanced (not amenable to curative therapy) or metastatic non-small cell lung cancer (NSCLC).

Citation

Pfizer Canada ULC. Xalkori (crizotinib) [product monograph]. Health Canada website. https://pdf.hres.ca/dpd_pm/00070448.PDF. Revised April 2023. Accessed June 2025.