PR negative
About
Biomarker Type: Protein expression
Present: True
Marker: Progesterone receptor (PR)
Unit: status
Equality: =
Value: Negative
Legacy biomarker representation, assumes GRCh37 / hg19 genome build.
Mappings
Therapeutic response
Precision oncology relationships for therapeutic response involving this biomarker.
| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | ER negative, HER2-negative, PR negative | Invasive Breast Carcinoma | Carboplatin, Cyclophosphamide, Doxorubicin, Paclitaxel, Pembrolizumab | |
| Sensitivity (+) | ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative | Invasive Breast Carcinoma | Paclitaxel, Pembrolizumab | |
| Sensitivity (+) | ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative | Invasive Breast Carcinoma | Carboplatin, Gemcitabine, Pembrolizumab | |
| Sensitivity (+) | ER negative, HER2-negative, PD-L1 >= 1%, PR negative | Invasive Breast Carcinoma | Atezolizumab, Nab-paclitaxel | |
| Sensitivity (+) | ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative | Invasive Breast Carcinoma | Paclitaxel, Pembrolizumab | |
| Sensitivity (+) | ER negative, HER2-negative, PR negative | Invasive Breast Carcinoma | Sacituzumab govitecan |