Any solid tumor

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OncoTree: Malignant Solid Neoplasm (ncit:C132146)

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Therapeutic response

Precision oncology relationships for therapeutic response involving this cancer type.

Type Biomarker(s) Cancer type Therapy(ies)
Sensitivity (+) BRAF p.V600E Any solid tumor Dabrafenib, Trametinib FDA
Sensitivity (+) dMMR Any solid tumor Dostarlimab FDA
Sensitivity (+) v::NTRK1 Any solid tumor Entrectinib FDA
Sensitivity (+) v::NTRK2 Any solid tumor Entrectinib FDA
Sensitivity (+) v::NTRK3 Any solid tumor Entrectinib FDA
Sensitivity (+) v::NTRK1 Any solid tumor Larotrectinib FDA
Sensitivity (+) v::NTRK2 Any solid tumor Larotrectinib FDA
Sensitivity (+) v::NTRK3 Any solid tumor Larotrectinib FDA
Sensitivity (+) dMMR Any solid tumor Pembrolizumab FDA
Sensitivity (+) MSI-H Any solid tumor Pembrolizumab FDA
Sensitivity (+) TMB-H (>= 10 mutations / Mb) Any solid tumor Pembrolizumab FDA
Sensitivity (+) v::NTRK1 Any solid tumor Repotrectinib FDA
Sensitivity (+) v::NTRK2 Any solid tumor Repotrectinib FDA
Sensitivity (+) v::NTRK3 Any solid tumor Repotrectinib FDA
Sensitivity (+) v::RET Any solid tumor Selpercatinib FDA
Sensitivity (+) BRAF p.V600E Any solid tumor Dabrafenib, Trametinib FDA
Sensitivity (+) HER2-positive Any solid tumor Trastuzumab deruxtecan FDA
Sensitivity (+) dMMR Any solid tumor Pembrolizumab HC
Sensitivity (+) MSI-H Any solid tumor Pembrolizumab HC
Sensitivity (+) v::NTRK1 Any solid tumor Entrectinib HC
Sensitivity (+) v::NTRK2 Any solid tumor Entrectinib HC
Sensitivity (+) v::NTRK3 Any solid tumor Entrectinib HC
Sensitivity (+) v::NTRK1 Any solid tumor Larotrectinib HC
Sensitivity (+) v::NTRK2 Any solid tumor Larotrectinib HC
Sensitivity (+) v::NTRK3 Any solid tumor Larotrectinib HC