Dabrafenib

About

Therapy type: Targeted therapy

Therapy strategy: B-RAF inhibition

Mappings

NCI Thesaurus: Dabrafenib (ncit:C82386)

Therapeutic response

Precision oncology relationships for therapeutic response involving this therapy.

Organization(s) Biomarker(s) Cancer type Therapy(ies)
FDA (1) HC (1) BRAF p.V600E Melanoma Dabrafenib
FDA (4) BRAF p.V600E Melanoma Dabrafenib, Trametinib
FDA (4) BRAF p.V600K Melanoma Dabrafenib, Trametinib
FDA (2) HC (2) BRAF p.V600E Non-Small Cell Lung Cancer Dabrafenib, Trametinib
FDA (2) BRAF p.V600E Anaplastic Thyroid Cancer Dabrafenib, Trametinib
FDA (2) BRAF p.V600E Any solid tumor Dabrafenib, Trametinib
FDA (2) HC (2) BRAF p.V600E Low-Grade Glioma, NOS Dabrafenib, Trametinib
HC (2) BRAF p.V600E High-Grade Glioma, NOS Dabrafenib, Trametinib
HC (1) BRAF p.V600K Melanoma Dabrafenib