ERBB2
About
Location: 17q12
Mappings
Biomarkers
ERBB2 is involved in the following curated biomarkers.
| Name | Biomarker type | Propositions | Statements |
|---|---|---|---|
| ERBB2 TKD activating variants | Somatic Variant | 1 | 1 |
| ERBB2 oncogenic variants | Somatic Variant | 1 | 1 |
| ERBB2 amplification | Copy Number |
Therapeutic response
Precision oncology relationships for therapeutic response involving this gene.
| Type | Biomarker(s) | Cancer type | Therapy(ies) | |
|---|---|---|---|---|
| Sensitivity (+) | ERBB2 oncogenic variants | Non-Small Cell Lung Cancer | Trastuzumab deruxtecan | |
| Sensitivity (+) | ERBB2 TKD activating variants | Lung Non-Squamous Non-Small Cell Carcinoma | Zongertinib |