PIK3CA

About

Location: 3q26.32

Mappings

HGNC: HGNC:8975

Ensembl: ENSG00000121879

NCBI: 5290

Refseq: NM_006218.4

View API

Biomarkers

PIK3CA is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
PIK3CA Somatic variants Somatic variant 9 17
PIK3CA Somatic variants Somatic variant
PIK3CA amplification Copy number 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organizations Biomarkers Cancer types Therapies
FDA (1) HC (1) ER positive, HER2-negative, PIK3CA Somatic variants Invasive Breast Carcinoma Alpelisib, Fulvestrant
FDA (1) HC (1) HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Alpelisib, Fulvestrant
FDA (1) HC (1) ER positive, HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Alpelisib, Fulvestrant
FDA (1) ER positive, HER2-negative, PIK3CA Somatic variants Invasive Breast Carcinoma Capivasertib, Fulvestrant
FDA (1) HC (1) HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Capivasertib, Fulvestrant
FDA (1) HC (1) ER positive, HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Capivasertib, Fulvestrant
FDA (1) HC (1) ER positive, HER2-negative, PIK3CA Somatic variants Invasive Breast Carcinoma Fulvestrant, Inavolisib, Palbociclib
FDA (1) HC (1) HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Fulvestrant, Inavolisib, Palbociclib
FDA (1) HC (1) ER positive, HER2-negative, PIK3CA Somatic variants, PR positive Invasive Breast Carcinoma Fulvestrant, Inavolisib, Palbociclib
HC (1) ER positive, HER2-negative, PIK3CA amplification Invasive Breast Carcinoma Capivasertib, Fulvestrant