RET
About
Location: 10q11.21
Mappings
Biomarkers
RET is involved in the following curated biomarkers.
| Name | Biomarker type | Propositions | Statements |
|---|---|---|---|
| v::RET | Gene fusion | 6 | 7 |
| RET p.M918T | Somatic variant | ||
| RET oncogenic variants | Somatic variant | 1 | 2 |
Therapeutic response
Precision oncology relationships for therapeutic response involving this gene.
| Organizations | Biomarkers | Cancer types | Therapies | |
|---|---|---|---|---|
| FDA (1) | v::RET | Non-Small Cell Lung Cancer | Pralsetinib | |
| FDA (1) | v::RET | Papillary Thyroid Cancer | Pralsetinib | |
| FDA (1) HC (1) | v::RET | Non-Small Cell Lung Cancer | Selpercatinib | |
| FDA (1) HC (1) | RET oncogenic variants | Medullary Thyroid Cancer | Selpercatinib | |
| FDA (1) | v::RET | Anaplastic Thyroid Cancer | Selpercatinib | |
| FDA (1) | v::RET | Any solid tumor | Selpercatinib | |
| HC (1) | v::RET | Papillary Thyroid Cancer | Selpercatinib |