Molecular Oncology Almanac
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    2. prop:vtxr:875

    Therapeutic Response

    ER positive, ESR1 activating variants, and HER2-negative status confers therapeutic sensitivity to Imlunestrant in patients with Invasive Breast Carcinoma.

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    Statements

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    Inluriyo (imlunestrant) [package insert]. FDA.

    The U.S. Food and Drug Administration (FDA) granted approval to imlunestrant for the treatment of adult patients with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.

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