| prop:vtxr:0 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Tamoxifen
|
|
| prop:vtxr:1 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Tamoxifen
|
|
| prop:vtxr:2 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Tamoxifen
|
|
| prop:vtxr:3 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Anastrozole
|
|
| prop:vtxr:4 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Anastrozole
|
|
| prop:vtxr:5 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Anastrozole
|
|
| prop:vtxr:6 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Letrozole
|
|
| prop:vtxr:7 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Letrozole
|
|
| prop:vtxr:8 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Letrozole
|
|
| prop:vtxr:9 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Fulvestrant
|
|
| prop:vtxr:10 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Fulvestrant
|
|
| prop:vtxr:11 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Fulvestrant
|
|
| prop:vtxr:12 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib
|
|
| prop:vtxr:13 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib
|
|
| prop:vtxr:14 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib
|
|
| prop:vtxr:15 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisone
|
|
| prop:vtxr:16 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisone
|
|
| prop:vtxr:17 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisone
|
|
| prop:vtxr:18 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisone
|
|
| prop:vtxr:19 |
Sensitivity |
KRAS p.G12C
|
Non-Small Cell Lung Cancer |
Adagrasib
|
|
| prop:vtxr:20 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Trastuzumab emtansine
|
|
| prop:vtxr:21 |
Sensitivity |
EGFR Somatic variants
|
Non-Small Cell Lung Cancer |
Afatinib
|
|
| prop:vtxr:22 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Alectinib
|
|
| prop:vtxr:23 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:24 |
Sensitivity |
HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:25 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:26 |
Sensitivity |
EGFR Exon 20 (Insertion)
|
Non-Small Cell Lung Cancer |
Amivantamab,
Carboplatin,
Pemetrexed
|
|
| prop:vtxr:27 |
Sensitivity |
EGFR Exon 20 (Insertion)
|
Non-Small Cell Lung Cancer |
Amivantamab
|
|
| prop:vtxr:28 |
Sensitivity |
PML::RARA
|
APL with PML-RARA |
Arsenic trioxide
|
|
| prop:vtxr:29 |
Sensitivity |
BCR::ABL1
|
Chronic Myelogenous Leukemia |
Asciminib
|
|
| prop:vtxr:30 |
Sensitivity |
ABL1 p.T315I, BCR::ABL1
|
Chronic Myelogenous Leukemia |
Asciminib
|
|
| prop:vtxr:31 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:32 |
Sensitivity |
PD-L1 >= 50%
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:33 |
Sensitivity |
PD-L1 >= 10% TIIC
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:34 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Bevacizumab,
Carboplatin,
Paclitaxel
|
|
| prop:vtxr:35 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Carboplatin,
Paclitaxel
|
|
| prop:vtxr:36 |
Sensitivity |
EGFR Somatic variants
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:37 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:38 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Atezolizumab,
Cobimetinib,
Vemurafenib
|
|
| prop:vtxr:39 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Atezolizumab,
Cobimetinib,
Vemurafenib
|
|
| prop:vtxr:40 |
Sensitivity |
PDGFRA p.D842V
|
Gastrointestinal Stromal Tumor |
Avapritinib
|
|
| prop:vtxr:41 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Binimetinib,
Encorafenib
|
|
| prop:vtxr:42 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Binimetinib,
Encorafenib
|
|
| prop:vtxr:43 |
Sensitivity |
BRAF p.V600E
|
Non-Small Cell Lung Cancer |
Binimetinib,
Encorafenib
|
|
| prop:vtxr:45 |
Sensitivity |
CD19 +
|
Acute Lymphoid Leukemia |
Blinatumomab
|
|
| prop:vtxr:46 |
Sensitivity |
CD19 +, not BCR::ABL1
|
Acute Lymphoid Leukemia |
Blinatumomab
|
|
| prop:vtxr:47 |
Sensitivity |
BCR::ABL1
|
Chronic Myelogenous Leukemia |
Bosutinib
|
|
| prop:vtxr:48 |
Sensitivity |
CD30 +
|
Anaplastic Large Cell Lymphoma |
Brentuximab vedotin,
Cyclophosphamide,
Doxorubicin,
Prednisone
|
|
| prop:vtxr:49 |
Sensitivity |
CD30 +
|
Anaplastic Large Cell Lymphoma |
Brentuximab vedotin
|
|
| prop:vtxr:50 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Brigatinib
|
|
| prop:vtxr:51 |
Sensitivity |
HER2-positive
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine
|
|
| prop:vtxr:52 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:53 |
Sensitivity |
HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:54 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:55 |
Sensitivity |
AKT1 Somatic variants, ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:56 |
Sensitivity |
AKT1 Somatic variants, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:57 |
Sensitivity |
AKT1 Somatic variants, ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:58 |
Sensitivity |
AKT1 amplification, ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:59 |
Sensitivity |
AKT1 amplification, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:60 |
Sensitivity |
AKT1 amplification, ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:61 |
Sensitivity |
ER positive, HER2-negative, PTEN nonsense variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:62 |
Sensitivity |
HER2-negative, PR positive, PTEN nonsense variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:63 |
Sensitivity |
ER positive, HER2-negative, PR positive, PTEN nonsense variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:64 |
Sensitivity |
ER positive, HER2-negative, PTEN frameshift variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:65 |
Sensitivity |
HER2-negative, PR positive, PTEN frameshift variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:66 |
Sensitivity |
ER positive, HER2-negative, PR positive, PTEN frameshift variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:67 |
Sensitivity |
ER positive, HER2-negative, PTEN splice site variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:68 |
Sensitivity |
HER2-negative, PR positive, PTEN splice site variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:69 |
Sensitivity |
ER positive, HER2-negative, PR positive, PTEN splice site variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:70 |
Sensitivity |
ER positive, HER2-negative, PTEN deletion
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:71 |
Sensitivity |
HER2-negative, PR positive, PTEN deletion
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:72 |
Sensitivity |
ER positive, HER2-negative, PR positive, PTEN deletion
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:73 |
Sensitivity |
MET Exon 14 (Splice Site)
|
Non-Small Cell Lung Cancer |
Capmatinib
|
|
| prop:vtxr:74 |
Sensitivity |
MET Exon 14 (Deletion)
|
Non-Small Cell Lung Cancer |
Capmatinib
|
|
| prop:vtxr:75 |
Sensitivity |
Wild type ALK, Wild type EGFR, Wild type ROS1
|
Non-Small Cell Lung Cancer |
Carboplatin,
Cemiplimab,
Pemetrexed
|
|
| prop:vtxr:76 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR, dMMR
|
Non-Small Cell Lung Cancer |
Cemiplimab
|
|
| prop:vtxr:77 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Ceritinib
|
|
| prop:vtxr:78 |
Sensitivity |
EGFR positive, Wild type KRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Fluorouracil,
Irinotecan
|
|
| prop:vtxr:79 |
Sensitivity |
EGFR positive, Wild type KRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Irinotecan
|
|
| prop:vtxr:80 |
Sensitivity |
EGFR positive, Wild type KRAS
|
Colorectal Adenocarcinoma |
Cetuximab
|
|
| prop:vtxr:81 |
Sensitivity |
BRAF p.V600E
|
Colorectal Adenocarcinoma |
Cetuximab,
Encorafenib
|
|
| prop:vtxr:82 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Cobimetinib,
Vemurafenib
|
|
| prop:vtxr:83 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Cobimetinib,
Vemurafenib
|
|
| prop:vtxr:84 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Crizotinib
|
|
| prop:vtxr:85 |
Sensitivity |
v::ROS1
|
Non-Small Cell Lung Cancer |
Crizotinib
|
|
| prop:vtxr:86 |
Sensitivity |
v::ALK
|
Anaplastic Large Cell Lymphoma |
Crizotinib
|
|
| prop:vtxr:87 |
Sensitivity |
v::ALK
|
Inflammatory Myofibroblastic Tumor |
Crizotinib
|
|
| prop:vtxr:88 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Dabrafenib
|
|
| prop:vtxr:89 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:90 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:91 |
Sensitivity |
BRAF p.V600E
|
Non-Small Cell Lung Cancer |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:92 |
Sensitivity |
BRAF p.V600E
|
Anaplastic Thyroid Cancer |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:93 |
Sensitivity |
BRAF p.V600E
|
Any solid tumor |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:94 |
Sensitivity |
BRAF p.V600E
|
Low-Grade Glioma, NOS |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:95 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Dacomitinib
|
|
| prop:vtxr:96 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Dacomitinib
|
|
| prop:vtxr:97 |
Sensitivity |
BCR::ABL1
|
Chronic Myelogenous Leukemia |
Dasatinib
|
|
| prop:vtxr:98 |
Sensitivity |
BCR::ABL1
|
Chronic Myeloid Leukemia, BCR-ABL1+ |
Dasatinib
|
|
| prop:vtxr:99 |
Sensitivity |
BCR::ABL1
|
Acute Lymphoid Leukemia |
Dasatinib
|
|
| prop:vtxr:100 |
Sensitivity |
dMMR
|
Endometrial Carcinoma |
Carboplatin,
Dostarlimab,
Paclitaxel
|
|
| prop:vtxr:101 |
Sensitivity |
MSI-H
|
Endometrial Carcinoma |
Carboplatin,
Dostarlimab,
Paclitaxel
|
|
| prop:vtxr:102 |
Sensitivity |
dMMR
|
Endometrial Carcinoma |
Dostarlimab
|
|
| prop:vtxr:103 |
Sensitivity |
dMMR
|
Any solid tumor |
Dostarlimab
|
|
| prop:vtxr:104 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Pemetrexed,
Tremelimumab
|
|
| prop:vtxr:105 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Durvalumab,
Pemetrexed,
Tremelimumab
|
|
| prop:vtxr:106 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Gemcitabine,
Tremelimumab
|
|
| prop:vtxr:107 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Durvalumab,
Gemcitabine,
Tremelimumab
|
|
| prop:vtxr:108 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Nab-paclitaxel,
Tremelimumab
|
|
| prop:vtxr:109 |
Sensitivity |
dMMR
|
Endometrial Carcinoma |
Carboplatin,
Durvalumab,
Paclitaxel
|
|
| prop:vtxr:110 |
Sensitivity |
ER positive, ESR1 activating variants, HER2-negative
|
Invasive Breast Carcinoma |
Elacestrant
|
|
| prop:vtxr:111 |
Sensitivity |
IDH2 p.R140Q
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:112 |
Sensitivity |
IDH2 p.R140L
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:113 |
Sensitivity |
IDH2 p.R140G
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:114 |
Sensitivity |
IDH2 p.R140W
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:115 |
Sensitivity |
IDH2 p.R172K
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:116 |
Sensitivity |
IDH2 p.R172M
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:117 |
Sensitivity |
IDH2 p.R172G
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:118 |
Sensitivity |
IDH2 p.R172S
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:119 |
Sensitivity |
IDH2 p.R172W
|
Acute Myeloid Leukemia |
Enasidenib
|
|
| prop:vtxr:120 |
Sensitivity |
v::ROS1
|
Non-Small Cell Lung Cancer |
Entrectinib
|
|
| prop:vtxr:121 |
Sensitivity |
v::NTRK1
|
Any solid tumor |
Entrectinib
|
|
| prop:vtxr:122 |
Sensitivity |
v::NTRK2
|
Any solid tumor |
Entrectinib
|
|
| prop:vtxr:123 |
Sensitivity |
v::NTRK3
|
Any solid tumor |
Entrectinib
|
|
| prop:vtxr:124 |
Sensitivity |
FGFR3 p.R248C
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:125 |
Sensitivity |
FGFR3 p.S249C
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:126 |
Sensitivity |
FGFR3 p.G370C
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:127 |
Sensitivity |
FGFR3 p.Y373C
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:128 |
Sensitivity |
FGFR3::TACC3
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:129 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Erlotinib
|
|
| prop:vtxr:130 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Erlotinib
|
|
| prop:vtxr:131 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Everolimus,
Exemestane
|
|
| prop:vtxr:132 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Everolimus,
Exemestane
|
|
| prop:vtxr:133 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Everolimus,
Exemestane
|
|
| prop:vtxr:134 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:135 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:136 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:137 |
Sensitivity |
ER positive
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:138 |
Sensitivity |
PR positive
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:139 |
Sensitivity |
ER positive, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:140 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Fulvestrant,
Ribociclib
|
|
| prop:vtxr:141 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Ribociclib
|
|
| prop:vtxr:142 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Ribociclib
|
|
| prop:vtxr:143 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Fulvestrant,
Palbociclib
|
|
| prop:vtxr:144 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Palbociclib
|
|
| prop:vtxr:145 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Palbociclib
|
|
| prop:vtxr:146 |
Sensitivity |
FGFR2::v
|
Intrahepatic Cholangiocarcinoma |
Futibatinib
|
|
| prop:vtxr:147 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Gefitinib
|
|
| prop:vtxr:148 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Gefitinib
|
|
| prop:vtxr:149 |
Sensitivity |
CD33 +
|
Acute Lymphoid Leukemia |
Gemtuzumab ozogamicin
|
|
| prop:vtxr:150 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:151 |
Sensitivity |
FLT3 p.D835Y
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:152 |
Sensitivity |
FLT3 p.D835A
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:153 |
Sensitivity |
FLT3 p.D835E
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:154 |
Sensitivity |
FLT3 p.D835H
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:155 |
Sensitivity |
FLT3 p.D835N
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:156 |
Sensitivity |
FLT3 p.D835S
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:157 |
Sensitivity |
FLT3 p.D835V
|
Acute Myeloid Leukemia |
Gilteritinib
|
|
| prop:vtxr:158 |
Sensitivity |
BCR::ABL1
|
Chronic Myelogenous Leukemia |
Imatinib
|
|
| prop:vtxr:159 |
Sensitivity |
BCR::ABL1
|
Chronic Myeloid Leukemia, BCR-ABL1+ |
Imatinib
|
|
| prop:vtxr:160 |
Sensitivity |
BCR::ABL1
|
Acute Lymphoid Leukemia |
Imatinib
|
|
| prop:vtxr:161 |
Sensitivity |
PDGFRA rearrangements
|
Myelodysplastic Syndromes |
Imatinib
|
|
| prop:vtxr:162 |
Sensitivity |
PDGFRB rearrangements
|
Myelodysplastic Syndromes |
Imatinib
|
|
| prop:vtxr:163 |
Sensitivity |
not KIT p.D816V
|
Aggressive Systemic Mastocytosis |
Imatinib
|
|
| prop:vtxr:164 |
Sensitivity |
FIP1L1::PDGFRA
|
Chronic Eosinophilic Leukemia, NOS |
Imatinib
|
|
| prop:vtxr:165 |
Sensitivity |
CD117 +
|
Gastrointestinal Stromal Tumor |
Imatinib
|
|
| prop:vtxr:166 |
Sensitivity |
FIP1L1::PDGFRA
|
Gastrointestinal Stromal Tumor |
Imatinib
|
|
| prop:vtxr:167 |
Sensitivity |
FGFR2::v
|
Cholangiocarcinoma |
Infigratinib
|
|
| prop:vtxr:168 |
Sensitivity |
CD22 +
|
Acute Lymphoid Leukemia |
Inotuzumab ozogamicin
|
|
| prop:vtxr:169 |
Sensitivity |
MSI-H
|
Colorectal Adenocarcinoma |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:170 |
Sensitivity |
pMMR
|
Colorectal Adenocarcinoma |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:171 |
Sensitivity |
PD-L1 >= 1%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:172 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Ipilimumab,
Nivolumab,
Pemetrexed
|
|
| prop:vtxr:173 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Ipilimumab,
Nivolumab,
Pemetrexed
|
|
| prop:vtxr:174 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Ipilimumab,
Nivolumab,
Paclitaxel
|
|
| prop:vtxr:175 |
Sensitivity |
IDH1 p.R132C
|
Acute Myeloid Leukemia |
Ivosidenib
|
|
| prop:vtxr:176 |
Sensitivity |
IDH1 p.R132G
|
Acute Myeloid Leukemia |
Ivosidenib
|
|
| prop:vtxr:177 |
Sensitivity |
IDH1 p.R132H
|
Acute Myeloid Leukemia |
Ivosidenib
|
|
| prop:vtxr:178 |
Sensitivity |
IDH1 p.R132L
|
Acute Myeloid Leukemia |
Ivosidenib
|
|
| prop:vtxr:179 |
Sensitivity |
IDH1 p.R132S
|
Acute Myeloid Leukemia |
Ivosidenib
|
|
| prop:vtxr:180 |
Sensitivity |
IDH1 p.R132C
|
Acute Myeloid Leukemia |
Azacitidine,
Ivosidenib
|
|
| prop:vtxr:181 |
Sensitivity |
IDH1 p.R132G
|
Acute Myeloid Leukemia |
Azacitidine,
Ivosidenib
|
|
| prop:vtxr:182 |
Sensitivity |
IDH1 p.R132H
|
Acute Myeloid Leukemia |
Azacitidine,
Ivosidenib
|
|
| prop:vtxr:183 |
Sensitivity |
IDH1 p.R132L
|
Acute Myeloid Leukemia |
Azacitidine,
Ivosidenib
|
|
| prop:vtxr:184 |
Sensitivity |
IDH1 p.R132S
|
Acute Myeloid Leukemia |
Azacitidine,
Ivosidenib
|
|
| prop:vtxr:185 |
Sensitivity |
IDH1 p.R132C
|
Myelodysplastic Syndromes |
Ivosidenib
|
|
| prop:vtxr:186 |
Sensitivity |
IDH1 p.R132G
|
Myelodysplastic Syndromes |
Ivosidenib
|
|
| prop:vtxr:187 |
Sensitivity |
IDH1 p.R132H
|
Myelodysplastic Syndromes |
Ivosidenib
|
|
| prop:vtxr:188 |
Sensitivity |
IDH1 p.R132L
|
Myelodysplastic Syndromes |
Ivosidenib
|
|
| prop:vtxr:189 |
Sensitivity |
IDH1 p.R132S
|
Myelodysplastic Syndromes |
Ivosidenib
|
|
| prop:vtxr:190 |
Sensitivity |
IDH1 p.R132C
|
Cholangiocarcinoma |
Ivosidenib
|
|
| prop:vtxr:191 |
Sensitivity |
IDH1 p.R132G
|
Cholangiocarcinoma |
Ivosidenib
|
|
| prop:vtxr:192 |
Sensitivity |
IDH1 p.R132H
|
Cholangiocarcinoma |
Ivosidenib
|
|
| prop:vtxr:193 |
Sensitivity |
IDH1 p.R132L
|
Cholangiocarcinoma |
Ivosidenib
|
|
| prop:vtxr:194 |
Sensitivity |
IDH1 p.R132S
|
Cholangiocarcinoma |
Ivosidenib
|
|
| prop:vtxr:195 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Capecitabine,
Lapatinib
|
|
| prop:vtxr:196 |
Sensitivity |
ER positive, HER2-positive
|
Invasive Breast Carcinoma |
Lapatinib,
Letrozole
|
|
| prop:vtxr:197 |
Sensitivity |
HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Lapatinib,
Letrozole
|
|
| prop:vtxr:198 |
Sensitivity |
ER positive, HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Lapatinib,
Letrozole
|
|
| prop:vtxr:199 |
Sensitivity |
v::NTRK1
|
Any solid tumor |
Larotrectinib
|
|
| prop:vtxr:200 |
Sensitivity |
v::NTRK2
|
Any solid tumor |
Larotrectinib
|
|
| prop:vtxr:201 |
Sensitivity |
v::NTRK3
|
Any solid tumor |
Larotrectinib
|
|
| prop:vtxr:202 |
Sensitivity |
5q deletion
|
Myelodysplastic Syndromes |
Lenalidomide
|
|
| prop:vtxr:203 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Lorlatinib
|
|
| prop:vtxr:204 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Capecitabine,
Margetuximab
|
|
| prop:vtxr:205 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Eribulin,
Margetuximab
|
|
| prop:vtxr:206 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Gemcitabine,
Margetuximab
|
|
| prop:vtxr:207 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Margetuximab,
Vinorelbine
|
|
| prop:vtxr:208 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:209 |
Sensitivity |
FLT3 p.D835Y
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:210 |
Sensitivity |
FLT3 p.D835A
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:211 |
Sensitivity |
FLT3 p.D835E
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:212 |
Sensitivity |
FLT3 p.D835H
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:213 |
Sensitivity |
FLT3 p.D835N
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:214 |
Sensitivity |
FLT3 p.D835S
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:215 |
Sensitivity |
FLT3 p.D835V
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:216 |
Sensitivity |
FLT3 p.I836del
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:217 |
Sensitivity |
CDK12 oncogenic variants
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Midostaurin
|
|
| prop:vtxr:218 |
Sensitivity |
EGFR Exon 20 (Insertion)
|
Non-Small Cell Lung Cancer |
Mobocertinib
|
|
| prop:vtxr:219 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:220 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Capecitabine,
Neratinib
|
|
| prop:vtxr:221 |
Sensitivity |
BCR::ABL1
|
Chronic Myelogenous Leukemia |
Nilotinib
|
|
| prop:vtxr:222 |
Sensitivity |
BCR::ABL1
|
Chronic Myeloid Leukemia, BCR-ABL1+ |
Nilotinib
|
|
| prop:vtxr:223 |
Sensitivity |
BRCA1 pathogenic variants
|
Ovarian Epithelial Tumor |
Niraparib
|
|
| prop:vtxr:224 |
Sensitivity |
BRCA2 pathogenic variants
|
Ovarian Epithelial Tumor |
Niraparib
|
|
| prop:vtxr:225 |
Sensitivity |
BRCA1 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Niraparib
|
|
| prop:vtxr:226 |
Sensitivity |
BRCA2 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Niraparib
|
|
| prop:vtxr:227 |
Sensitivity |
BRCA1 pathogenic variants
|
Peritoneal Serous Carcinoma |
Niraparib
|
|
| prop:vtxr:228 |
Sensitivity |
BRCA2 pathogenic variants
|
Peritoneal Serous Carcinoma |
Niraparib
|
|
| prop:vtxr:229 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Nivolumab,
Paclitaxel
|
|
| prop:vtxr:230 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:231 |
Sensitivity |
BRCA1 oncogenic variants
|
Ovarian Epithelial Tumor |
Olaparib
|
|
| prop:vtxr:232 |
Sensitivity |
BRCA1 pathogenic variants
|
Ovarian Epithelial Tumor |
Olaparib
|
|
| prop:vtxr:233 |
Sensitivity |
BRCA2 oncogenic variants
|
Ovarian Epithelial Tumor |
Olaparib
|
|
| prop:vtxr:234 |
Sensitivity |
BRCA2 pathogenic variants
|
Ovarian Epithelial Tumor |
Olaparib
|
|
| prop:vtxr:235 |
Sensitivity |
BRCA1 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Olaparib
|
|
| prop:vtxr:236 |
Sensitivity |
BRCA1 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Olaparib
|
|
| prop:vtxr:237 |
Sensitivity |
BRCA2 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Olaparib
|
|
| prop:vtxr:238 |
Sensitivity |
BRCA2 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Olaparib
|
|
| prop:vtxr:239 |
Sensitivity |
BRCA1 oncogenic variants
|
Peritoneal Serous Carcinoma |
Olaparib
|
|
| prop:vtxr:240 |
Sensitivity |
BRCA1 pathogenic variants
|
Peritoneal Serous Carcinoma |
Olaparib
|
|
| prop:vtxr:241 |
Sensitivity |
BRCA2 oncogenic variants
|
Peritoneal Serous Carcinoma |
Olaparib
|
|
| prop:vtxr:242 |
Sensitivity |
BRCA2 pathogenic variants
|
Peritoneal Serous Carcinoma |
Olaparib
|
|
| prop:vtxr:243 |
Sensitivity |
BRCA1 oncogenic variants
|
Ovarian Epithelial Tumor |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:244 |
Sensitivity |
BRCA1 pathogenic variants
|
Ovarian Epithelial Tumor |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:245 |
Sensitivity |
BRCA2 oncogenic variants
|
Ovarian Epithelial Tumor |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:246 |
Sensitivity |
BRCA2 pathogenic variants
|
Ovarian Epithelial Tumor |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:247 |
Sensitivity |
HRD
|
Ovarian Epithelial Tumor |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:248 |
Sensitivity |
BRCA1 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:249 |
Sensitivity |
BRCA1 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:250 |
Sensitivity |
BRCA2 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:251 |
Sensitivity |
BRCA2 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:252 |
Sensitivity |
HRD
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:253 |
Sensitivity |
BRCA1 oncogenic variants
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:254 |
Sensitivity |
BRCA1 pathogenic variants
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:255 |
Sensitivity |
BRCA2 oncogenic variants
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:256 |
Sensitivity |
BRCA2 pathogenic variants
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:257 |
Sensitivity |
HRD
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Olaparib
|
|
| prop:vtxr:258 |
Sensitivity |
BRCA1 pathogenic variants, HER2-negative
|
Invasive Breast Carcinoma |
Olaparib
|
|
| prop:vtxr:259 |
Sensitivity |
BRCA2 pathogenic variants, HER2-negative
|
Invasive Breast Carcinoma |
Olaparib
|
|
| prop:vtxr:260 |
Sensitivity |
BRCA1 pathogenic variants
|
Pancreatic Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:261 |
Sensitivity |
BRCA2 pathogenic variants
|
Pancreatic Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:262 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:263 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:264 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:265 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:266 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:267 |
Sensitivity |
ATM pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:268 |
Sensitivity |
ATM oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:269 |
Sensitivity |
BARD1 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:270 |
Sensitivity |
BARD1 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:271 |
Sensitivity |
BRIP1 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:272 |
Sensitivity |
BRIP1 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:273 |
Sensitivity |
CDK12 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:274 |
Sensitivity |
CDK12 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:275 |
Sensitivity |
CHEK1 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:276 |
Sensitivity |
CHEK1 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:277 |
Sensitivity |
CHEK2 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:278 |
Sensitivity |
CHEK2 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:279 |
Sensitivity |
FANCL pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:280 |
Sensitivity |
FANCL oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:281 |
Sensitivity |
PALB2 pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:282 |
Sensitivity |
PALB2 oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:283 |
Sensitivity |
RAD51B pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:284 |
Sensitivity |
RAD51B oncogenic variants
|
Prostate Adenocarcinoma |
Talazoparib
|
|
| prop:vtxr:285 |
Sensitivity |
RAD51C pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:286 |
Sensitivity |
RAD51C oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:287 |
Sensitivity |
RAD51D pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:288 |
Sensitivity |
RAD51D oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:289 |
Sensitivity |
RAD54L pathogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:290 |
Sensitivity |
RAD54L oncogenic variants
|
Prostate Adenocarcinoma |
Olaparib
|
|
| prop:vtxr:291 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisolone
|
|
| prop:vtxr:292 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisolone
|
|
| prop:vtxr:293 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisolone
|
|
| prop:vtxr:294 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisolone
|
|
| prop:vtxr:295 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisone
|
|
| prop:vtxr:296 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisone
|
|
| prop:vtxr:297 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisone
|
|
| prop:vtxr:298 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Olaparib,
Prednisone
|
|
| prop:vtxr:299 |
Sensitivity |
IDH1 p.R132C
|
Acute Myeloid Leukemia |
Olutasidenib
|
|
| prop:vtxr:300 |
Sensitivity |
IDH1 p.R132G
|
Acute Myeloid Leukemia |
Olutasidenib
|
|
| prop:vtxr:301 |
Sensitivity |
IDH1 p.R132H
|
Acute Myeloid Leukemia |
Olutasidenib
|
|
| prop:vtxr:302 |
Sensitivity |
IDH1 p.R132L
|
Acute Myeloid Leukemia |
Olutasidenib
|
|
| prop:vtxr:303 |
Sensitivity |
IDH1 p.R132S
|
Acute Myeloid Leukemia |
Olutasidenib
|
|
| prop:vtxr:304 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Osimertinib
|
|
| prop:vtxr:305 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Osimertinib
|
|
| prop:vtxr:306 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Cisplatin,
Osimertinib,
Pemetrexed
|
|
| prop:vtxr:307 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Carboplatin,
Osimertinib,
Pemetrexed
|
|
| prop:vtxr:308 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Carboplatin,
Osimertinib,
Pemetrexed
|
|
| prop:vtxr:309 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Cisplatin,
Osimertinib,
Pemetrexed
|
|
| prop:vtxr:310 |
Sensitivity |
EGFR p.T790M
|
Non-Small Cell Lung Cancer |
Osimertinib
|
|
| prop:vtxr:311 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Letrozole,
Palbociclib
|
|
| prop:vtxr:312 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole,
Palbociclib
|
|
| prop:vtxr:313 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole,
Palbociclib
|
|
| prop:vtxr:314 |
Sensitivity |
Wild type HRAS, Wild type KRAS
|
Colorectal Adenocarcinoma |
Fluorouracil,
Oxaliplatin,
Panitumumab
|
|
| prop:vtxr:315 |
Sensitivity |
Wild type HRAS, Wild type KRAS
|
Colorectal Adenocarcinoma |
Panitumumab
|
|
| prop:vtxr:316 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Pembrolizumab,
Pemetrexed
|
|
| prop:vtxr:317 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Pembrolizumab,
Pemetrexed
|
|
| prop:vtxr:318 |
Sensitivity |
PD-L1 >= 1%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Pembrolizumab
|
|
| prop:vtxr:319 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Pembrolizumab
|
|
| prop:vtxr:320 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Head and Neck Squamous Cell Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:321 |
Sensitivity |
dMMR
|
Any solid tumor |
Pembrolizumab
|
|
| prop:vtxr:322 |
Sensitivity |
MSI-H
|
Any solid tumor |
Pembrolizumab
|
|
| prop:vtxr:323 |
Sensitivity |
dMMR
|
Colorectal Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:324 |
Sensitivity |
MSI-H
|
Colorectal Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:325 |
Sensitivity |
HER2-positive, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Pembrolizumab,
Trastuzumab
|
|
| prop:vtxr:326 |
Sensitivity |
HER2-positive, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Pembrolizumab,
Trastuzumab
|
|
| prop:vtxr:327 |
Sensitivity |
HER2-negative
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:328 |
Sensitivity |
HER2-negative
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Pembrolizumab
|
|
| prop:vtxr:329 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Adenocarcinoma of the Gastroesophageal Junction |
Pembrolizumab
|
|
| prop:vtxr:330 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Esophageal Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:331 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Adenocarcinoma |
Cisplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:332 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Squamous Cell Carcinoma |
Cisplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:333 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Adenocarcinoma |
Bevacizumab,
Cisplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:334 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Squamous Cell Carcinoma |
Bevacizumab,
Cisplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:335 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Adenocarcinoma |
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:336 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Squamous Cell Carcinoma |
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:337 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Adenocarcinoma |
Bevacizumab,
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:338 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Squamous Cell Carcinoma |
Bevacizumab,
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:339 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:340 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Cervical Squamous Cell Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:341 |
Sensitivity |
MSI-L
|
Endometrial Carcinoma |
Lenvatinib,
Pembrolizumab
|
|
| prop:vtxr:342 |
Sensitivity |
pMMR
|
Endometrial Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:343 |
Sensitivity |
MSI-H
|
Endometrial Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:344 |
Sensitivity |
TMB-H (>= 10 mutations / Mb)
|
Any solid tumor |
Pembrolizumab
|
|
| prop:vtxr:345 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Carboplatin,
Cyclophosphamide,
Doxorubicin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:346 |
Sensitivity |
ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative
|
Invasive Breast Carcinoma |
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:347 |
Sensitivity |
ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative
|
Invasive Breast Carcinoma |
Carboplatin,
Gemcitabine,
Pembrolizumab
|
|
| prop:vtxr:348 |
Sensitivity |
FGFR2::v
|
Cholangiocarcinoma |
Pemigatinib
|
|
| prop:vtxr:349 |
Sensitivity |
FGFR2 rearrangements
|
Cholangiocarcinoma |
Pemigatinib
|
|
| prop:vtxr:350 |
Sensitivity |
FGFR1 rearrangements
|
Myeloid/Lymphoid Neoplasms |
Pemigatinib
|
|
| prop:vtxr:351 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Docetaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:352 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Doxorubicin,
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:353 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Docetaxel,
Epirubicin,
Fluorouracil,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:354 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Epirubicin,
Fluorouracil,
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:355 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Docetaxel,
Doxorubicin,
Fluorouracil,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:356 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Doxorubicin,
Fluorouracil,
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:357 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Docetaxel,
Epirubicin,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:358 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Epirubicin,
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:359 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Docetaxel,
Doxorubicin,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:360 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Carboplatin,
Docetaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:361 |
Sensitivity |
BCR::ABL1
|
Acute Lymphoid Leukemia |
Cytarabine,
Dexamethasone,
Methotrexate,
Ponatinib,
Prednisone,
Vincristine
|
|
| prop:vtxr:362 |
Sensitivity |
ABL1 p.T315I, BCR::ABL1
|
Acute Lymphoid Leukemia |
Ponatinib
|
|
| prop:vtxr:363 |
Sensitivity |
ABL1 p.T315I
|
Chronic Myelogenous Leukemia |
Ponatinib
|
|
| prop:vtxr:364 |
Sensitivity |
v::RET
|
Non-Small Cell Lung Cancer |
Pralsetinib
|
|
| prop:vtxr:365 |
Sensitivity |
v::RET
|
Papillary Thyroid Cancer |
Pralsetinib
|
|
| prop:vtxr:366 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Erlotinib,
Ramucirumab
|
|
| prop:vtxr:367 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Erlotinib,
Ramucirumab
|
|
| prop:vtxr:368 |
Sensitivity |
v::ROS1
|
Non-Small Cell Lung Cancer |
Repotrectinib
|
|
| prop:vtxr:369 |
Sensitivity |
v::NTRK1
|
Any solid tumor |
Repotrectinib
|
|
| prop:vtxr:370 |
Sensitivity |
v::NTRK2
|
Any solid tumor |
Repotrectinib
|
|
| prop:vtxr:371 |
Sensitivity |
v::NTRK3
|
Any solid tumor |
Repotrectinib
|
|
| prop:vtxr:372 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Anastrozole,
Ribociclib
|
|
| prop:vtxr:373 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Ribociclib
|
|
| prop:vtxr:374 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Ribociclib
|
|
| prop:vtxr:375 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Letrozole,
Ribociclib
|
|
| prop:vtxr:376 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole,
Ribociclib
|
|
| prop:vtxr:377 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole,
Ribociclib
|
|
| prop:vtxr:378 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Rituximab
|
|
| prop:vtxr:379 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:380 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:381 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Fludarabine,
Mitoxantrone,
Rituximab
|
|
| prop:vtxr:382 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisone,
Rituximab,
Vincristine
|
|
| prop:vtxr:383 |
Sensitivity |
CD20 +
|
Diffuse Large B-Cell Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisone,
Rituximab,
Vincristine
|
|
| prop:vtxr:384 |
Sensitivity |
CD20 +
|
Burkitt Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisone,
Rituximab,
Vincristine
|
|
| prop:vtxr:385 |
Sensitivity |
CD20 +
|
Mature B-Cell Neoplasms |
Cyclophosphamide,
Doxorubicin,
Prednisone,
Rituximab,
Vincristine
|
|
| prop:vtxr:386 |
Sensitivity |
CD20 +
|
Chronic Lymphocytic Leukemia |
Cyclophosphamide,
Fludarabine,
Rituximab
|
|
| prop:vtxr:387 |
Sensitivity |
BRCA1 oncogenic variants
|
Ovarian Epithelial Tumor |
Rucaparib
|
|
| prop:vtxr:388 |
Sensitivity |
BRCA1 pathogenic variants
|
Ovarian Epithelial Tumor |
Rucaparib
|
|
| prop:vtxr:389 |
Sensitivity |
BRCA2 oncogenic variants
|
Ovarian Epithelial Tumor |
Rucaparib
|
|
| prop:vtxr:390 |
Sensitivity |
BRCA2 pathogenic variants
|
Ovarian Epithelial Tumor |
Rucaparib
|
|
| prop:vtxr:391 |
Sensitivity |
BRCA1 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Rucaparib
|
|
| prop:vtxr:392 |
Sensitivity |
BRCA1 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Rucaparib
|
|
| prop:vtxr:393 |
Sensitivity |
BRCA2 oncogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Rucaparib
|
|
| prop:vtxr:394 |
Sensitivity |
BRCA2 pathogenic variants
|
High-Grade Serous Fallopian Tube Cancer |
Rucaparib
|
|
| prop:vtxr:395 |
Sensitivity |
BRCA1 oncogenic variants
|
Peritoneal Serous Carcinoma |
Rucaparib
|
|
| prop:vtxr:396 |
Sensitivity |
BRCA1 pathogenic variants
|
Peritoneal Serous Carcinoma |
Rucaparib
|
|
| prop:vtxr:397 |
Sensitivity |
BRCA2 oncogenic variants
|
Peritoneal Serous Carcinoma |
Rucaparib
|
|
| prop:vtxr:398 |
Sensitivity |
BRCA2 pathogenic variants
|
Peritoneal Serous Carcinoma |
Rucaparib
|
|
| prop:vtxr:399 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Rucaparib
|
|
| prop:vtxr:400 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Rucaparib
|
|
| prop:vtxr:401 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Rucaparib
|
|
| prop:vtxr:402 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Rucaparib
|
|
| prop:vtxr:403 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Sacituzumab govitecan
|
|
| prop:vtxr:404 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Sacituzumab govitecan
|
|
| prop:vtxr:405 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Sacituzumab govitecan
|
|
| prop:vtxr:406 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Sacituzumab govitecan
|
|
| prop:vtxr:407 |
Sensitivity |
v::RET
|
Non-Small Cell Lung Cancer |
Selpercatinib
|
|
| prop:vtxr:408 |
Sensitivity |
RET oncogenic variants
|
Medullary Thyroid Cancer |
Selpercatinib
|
|
| prop:vtxr:409 |
Sensitivity |
v::RET
|
Anaplastic Thyroid Cancer |
Selpercatinib
|
|
| prop:vtxr:410 |
Sensitivity |
v::RET
|
Any solid tumor |
Selpercatinib
|
|
| prop:vtxr:411 |
Sensitivity |
KRAS p.G12C
|
Non-Small Cell Lung Cancer |
Sotorasib
|
|
| prop:vtxr:412 |
Sensitivity |
BRCA1 pathogenic variants, HER2-negative
|
Invasive Breast Carcinoma |
Talazoparib
|
|
| prop:vtxr:413 |
Sensitivity |
BRCA2 pathogenic variants, HER2-negative
|
Invasive Breast Carcinoma |
Talazoparib
|
|
| prop:vtxr:414 |
Sensitivity |
MET Exon 14 (Splice Site)
|
Non-Small Cell Lung Cancer |
Tepotinib
|
|
| prop:vtxr:415 |
Sensitivity |
MET Exon 14 (Deletion)
|
Non-Small Cell Lung Cancer |
Tepotinib
|
|
| prop:vtxr:416 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Trametinib
|
|
| prop:vtxr:417 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Trametinib
|
|
| prop:vtxr:418 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Trastuzumab
|
|
| prop:vtxr:419 |
Sensitivity |
HER2-positive
|
Gastrointestinal Stromal Tumor |
Trastuzumab
|
|
| prop:vtxr:420 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:421 |
Sensitivity |
HER2-low
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:422 |
Sensitivity |
ERBB2 activating variants
|
Non-Small Cell Lung Cancer |
Trastuzumab deruxtecan
|
|
| prop:vtxr:423 |
Sensitivity |
HER2-positive
|
Adenocarcinoma of the Gastroesophageal Junction |
Trastuzumab deruxtecan
|
|
| prop:vtxr:424 |
Sensitivity |
HER2-positive
|
Any solid tumor |
Trastuzumab deruxtecan
|
|
| prop:vtxr:425 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Capecitabine,
Trastuzumab,
Tucatinib
|
|
| prop:vtxr:426 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Vemurafenib
|
|
| prop:vtxr:427 |
Sensitivity |
BRAF p.V600E
|
Non-Langerhans Cell Histiocytosis/Erdheim-Chester Disease |
Vemurafenib
|
|
| prop:vtxr:428 |
Sensitivity |
BRAF p.V600K
|
Non-Langerhans Cell Histiocytosis/Erdheim-Chester Disease |
Vemurafenib
|
|
| prop:vtxr:429 |
Sensitivity |
EZH2 p.Y646N
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:430 |
Sensitivity |
EZH2 p.Y646F
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:431 |
Sensitivity |
EZH2 p.Y646H
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:432 |
Sensitivity |
EZH2 p.Y646S
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:433 |
Sensitivity |
EZH2 p.Y646C
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:434 |
Sensitivity |
EZH2 p.A682G
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:435 |
Sensitivity |
EZH2 p.A692V
|
Follicular Lymphoma |
Tazemetostat
|
|
| prop:vtxr:436 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:437 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:438 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:439 |
Sensitivity |
ATM pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:440 |
Sensitivity |
ATM oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:441 |
Sensitivity |
ATR oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:442 |
Sensitivity |
CDK12 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:443 |
Sensitivity |
ATR pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:444 |
Sensitivity |
FANCA oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:445 |
Sensitivity |
CHEK2 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:446 |
Sensitivity |
CHEK2 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:447 |
Sensitivity |
FANCA pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:448 |
Sensitivity |
MLH1 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:449 |
Sensitivity |
PALB2 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:450 |
Sensitivity |
PALB2 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:451 |
Sensitivity |
MLH1 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:452 |
Sensitivity |
MRE11 oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:453 |
Sensitivity |
RAD51C pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:454 |
Sensitivity |
RAD51C oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:455 |
Sensitivity |
MRE11 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:456 |
Sensitivity |
NBN oncogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:457 |
Sensitivity |
NBN pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:458 |
Sensitivity |
TSC1 oncogenic variants
|
Renal Angiomyolipoma |
Everolimus
|
|
| prop:vtxr:459 |
Sensitivity |
TSC2 oncogenic variants
|
Renal Angiomyolipoma |
Everolimus
|
|
| prop:vtxr:460 |
Sensitivity |
TSC1 oncogenic variants
|
Subependymal Giant Cell Astrocytoma |
Everolimus
|
|
| prop:vtxr:461 |
Sensitivity |
TSC2 oncogenic variants
|
Subependymal Giant Cell Astrocytoma |
Everolimus
|
|
| prop:vtxr:462 |
Sensitivity |
CDK12 pathogenic variants
|
Prostate Adenocarcinoma |
Enzalutamide,
Talazoparib
|
|
| prop:vtxr:463 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Amivantamab,
Lazertinib
|
|
| prop:vtxr:464 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Amivantamab,
Lazertinib
|
|
| prop:vtxr:465 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Amivantamab,
Carboplatin,
Pemetrexed
|
|
| prop:vtxr:466 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Amivantamab,
Carboplatin,
Pemetrexed
|
|
| prop:vtxr:467 |
Sensitivity |
FOLR1 positive
|
Ovarian Epithelial Tumor |
Mirvetuximab soravtansine
|
|
| prop:vtxr:468 |
Sensitivity |
FOLR1 positive
|
High-Grade Serous Fallopian Tube Cancer |
Mirvetuximab soravtansine
|
|
| prop:vtxr:469 |
Sensitivity |
FOLR1 positive
|
Peritoneal Serous Carcinoma |
Mirvetuximab soravtansine
|
|
| prop:vtxr:470 |
Sensitivity |
BRAF rearrangements
|
Low-Grade Glioma, NOS |
Tovorafenib
|
|
| prop:vtxr:471 |
Sensitivity |
v::BRAF
|
Low-Grade Glioma, NOS |
Tovorafenib
|
|
| prop:vtxr:472 |
Sensitivity |
BRAF p.V600E
|
Low-Grade Glioma, NOS |
Tovorafenib
|
|
| prop:vtxr:473 |
Sensitivity |
BRAF p.V600K
|
Low-Grade Glioma, NOS |
Tovorafenib
|
|
| prop:vtxr:474 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Paclitaxel
|
|
| prop:vtxr:475 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Durvalumab,
Gemcitabine
|
|
| prop:vtxr:476 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Durvalumab,
Pemetrexed
|
|
| prop:vtxr:477 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Pemetrexed
|
|
| prop:vtxr:478 |
Sensitivity |
KRAS p.G12C
|
Colorectal Adenocarcinoma |
Adagrasib,
Cetuximab
|
|
| prop:vtxr:479 |
Sensitivity |
IDH1 p.R132C
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:480 |
Sensitivity |
IDH1 p.R132G
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:481 |
Sensitivity |
IDH1 p.R132H
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:482 |
Sensitivity |
IDH1 p.R132L
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:483 |
Sensitivity |
IDH1 p.R132S
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:484 |
Sensitivity |
IDH2 p.R172K
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:485 |
Sensitivity |
IDH2 p.R172M
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:486 |
Sensitivity |
IDH2 p.R172G
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:487 |
Sensitivity |
IDH2 p.R172S
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:488 |
Sensitivity |
IDH2 p.R172W
|
Astrocytoma |
Vorasidenib
|
|
| prop:vtxr:489 |
Sensitivity |
IDH1 p.R132C
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:490 |
Sensitivity |
IDH1 p.R132G
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:491 |
Sensitivity |
IDH1 p.R132H
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:492 |
Sensitivity |
IDH1 p.R132L
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:493 |
Sensitivity |
IDH1 p.R132S
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:494 |
Sensitivity |
IDH2 p.R172K
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:495 |
Sensitivity |
IDH2 p.R172M
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:496 |
Sensitivity |
IDH2 p.R172G
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:497 |
Sensitivity |
IDH2 p.R172S
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:498 |
Sensitivity |
IDH2 p.R172W
|
Oligodendroglioma |
Vorasidenib
|
|
| prop:vtxr:499 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Anastrozole,
Goserelin,
Ribociclib
|
|
| prop:vtxr:500 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Goserelin,
Ribociclib
|
|
| prop:vtxr:501 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Goserelin,
Ribociclib
|
|
| prop:vtxr:502 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Goserelin,
Letrozole,
Ribociclib
|
|
| prop:vtxr:503 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Goserelin,
Letrozole,
Ribociclib
|
|
| prop:vtxr:504 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Goserelin,
Letrozole,
Ribociclib
|
|
| prop:vtxr:505 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Nivolumab,
Pemetrexed
|
|
| prop:vtxr:506 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Gemcitabine,
Nivolumab
|
|
| prop:vtxr:507 |
Sensitivity |
dMMR
|
Colorectal Adenocarcinoma |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:508 |
Sensitivity |
MSI-H
|
Colorectal Adenocarcinoma |
Nivolumab
|
|
| prop:vtxr:509 |
Sensitivity |
dMMR
|
Colorectal Adenocarcinoma |
Nivolumab
|
|
| prop:vtxr:510 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants
|
Invasive Breast Carcinoma |
Fulvestrant,
Inavolisib,
Palbociclib
|
|
| prop:vtxr:511 |
Sensitivity |
HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Inavolisib,
Palbociclib
|
|
| prop:vtxr:512 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Fulvestrant,
Inavolisib,
Palbociclib
|
|
| prop:vtxr:513 |
Sensitivity |
CLDN18.2 >= 75%, HER2-negative
|
Adenocarcinoma of the Gastroesophageal Junction |
Fluorouracil,
Oxaliplatin,
Zolbetuximab
|
|
| prop:vtxr:514 |
Sensitivity |
CLDN18.2 >= 75%, HER2-negative
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Zolbetuximab
|
|
| prop:vtxr:515 |
Sensitivity |
HER2-positive
|
Intraductal Papillary Neoplasm of the Bile Duct |
Zanidatamab
|
|
| prop:vtxr:516 |
Sensitivity |
HER2-positive
|
Intracholecystic Papillary Neoplasm |
Zanidatamab
|
|
| prop:vtxr:517 |
Sensitivity |
HER2-positive
|
Cholangiocarcinoma |
Zanidatamab
|
|
| prop:vtxr:518 |
Sensitivity |
v::NRG1
|
Non-Small Cell Lung Cancer |
Zenocutuzumab
|
|
| prop:vtxr:519 |
Sensitivity |
v::NRG1
|
Pancreatic Adenocarcinoma |
Zenocutuzumab
|
|
| prop:vtxr:520 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Ensartinib
|
|
| prop:vtxr:521 |
Sensitivity |
BRAF p.V600E
|
Colorectal Adenocarcinoma |
Cetuximab,
Encorafenib,
Fluorouracil,
Oxaliplatin
|
|
| prop:vtxr:522 |
Sensitivity |
BCR::ABL1
|
Chronic Myeloid Leukemia, BCR-ABL1+ |
Asciminib
|
|
| prop:vtxr:528 |
Sensitivity |
t(KMT2A;v)
|
Acute Lymphoid Leukemia |
Revumenib
|
|
| prop:vtxr:529 |
Sensitivity |
t(KMT2A;v)
|
Acute Myeloid Leukemia |
Revumenib
|
|
| prop:vtxr:530 |
Sensitivity |
t(KMT2A;v)
|
Burkitt Lymphoma |
Revumenib
|
|
| prop:vtxr:531 |
Sensitivity |
t(KMT2A;v)
|
Acute Leukemias of Ambiguous Lineage |
Revumenib
|
|
| prop:vtxr:532 |
Sensitivity |
CD30 +
|
Hodgkin Lymphoma |
Brentuximab vedotin,
Dacarbazine,
Doxorubicin,
Vinblastine
|
|
| prop:vtxr:533 |
Sensitivity |
CD30 +
|
Hodgkin Lymphoma |
Brentuximab vedotin
|
|
| prop:vtxr:534 |
Sensitivity |
CD30 +
|
Cutaneous T-cell Lymphoma |
Brentuximab vedotin
|
|
| prop:vtxr:537 |
Sensitivity |
BRCA1 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisolone
|
|
| prop:vtxr:538 |
Sensitivity |
BRCA2 oncogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisolone
|
|
| prop:vtxr:539 |
Sensitivity |
BRCA1 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisolone
|
|
| prop:vtxr:540 |
Sensitivity |
BRCA2 pathogenic variants
|
Prostate Adenocarcinoma |
Abiraterone acetate,
Niraparib,
Prednisolone
|
|
| prop:vtxr:541 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Bevacizumab,
Erlotinib
|
|
| prop:vtxr:542 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Bevacizumab,
Erlotinib
|
|
| prop:vtxr:543 |
Sensitivity |
CD22 +, not BCR::ABL1
|
Acute Lymphoid Leukemia |
Inotuzumab ozogamicin
|
|
| prop:vtxr:545 |
Sensitivity |
BCR::ABL1
|
Chronic Myeloid Leukemia, BCR-ABL1+ |
Bosutinib
|
|
| prop:vtxr:546 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Esophageal Adenocarcinoma |
Dordaviprone
|
|
| prop:vtxr:547 |
Sensitivity |
v::RET
|
Medullary Thyroid Cancer |
Vandetanib
|
|
| prop:vtxr:548 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Erlotinib,
Ramucirumab
|
|
| prop:vtxr:549 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Docetaxel,
Trastuzumab
|
|
| prop:vtxr:550 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Docetaxel,
Trastuzumab
|
|
| prop:vtxr:551 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:552 |
Sensitivity |
ERBB2 amplification
|
Non-Small Cell Lung Cancer |
Trastuzumab deruxtecan
|
|
| prop:vtxr:553 |
Sensitivity |
ERBB2 amplification
|
Adenocarcinoma of the Gastroesophageal Junction |
Trastuzumab deruxtecan
|
|
| prop:vtxr:554 |
Sensitivity |
EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab
|
|
| prop:vtxr:555 |
Sensitivity |
EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Irinotecan
|
|
| prop:vtxr:556 |
Sensitivity |
EGFR positive, Wild type HRAS, Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Fluorouracil,
Oxaliplatin
|
|
| prop:vtxr:559 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Gefitinib
|
|
| prop:vtxr:560 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Afatinib
|
|
| prop:vtxr:561 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:562 |
Sensitivity |
ER positive, HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:563 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Carboplatin,
Docetaxel,
Trastuzumab
|
|
| prop:vtxr:564 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Doxorubicin,
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:565 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Trastuzumab
|
|
| prop:vtxr:566 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:567 |
Sensitivity |
ER positive, HER2-positive
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:568 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Carboplatin,
Docetaxel,
Trastuzumab
|
|
| prop:vtxr:569 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Doxorubicin,
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:570 |
Sensitivity |
HER2-positive
|
Esophagogastric Adenocarcinoma |
Capecitabine,
Cisplatin,
Trastuzumab
|
|
| prop:vtxr:571 |
Sensitivity |
HER2-positive
|
Esophagogastric Adenocarcinoma |
Cisplatin,
Fluorouracil,
Trastuzumab
|
|
| prop:vtxr:572 |
Sensitivity |
ERBB2 amplification
|
Esophagogastric Adenocarcinoma |
Capecitabine,
Cisplatin,
Trastuzumab
|
|
| prop:vtxr:573 |
Sensitivity |
ERBB2 amplification
|
Esophagogastric Adenocarcinoma |
Cisplatin,
Fluorouracil,
Trastuzumab
|
|
| prop:vtxr:578 |
Sensitivity |
not BCR::ABL1
|
Chronic Myelogenous Leukemia |
Imatinib
|
|
| prop:vtxr:579 |
Sensitivity |
not BCR::ABL1
|
Acute Lymphoid Leukemia |
Imatinib
|
|
| prop:vtxr:580 |
Sensitivity |
PDGFRA rearrangements
|
Myeloproliferative Neoplasm |
Imatinib
|
|
| prop:vtxr:581 |
Sensitivity |
PDGFRB rearrangements
|
Myeloproliferative Neoplasm |
Imatinib
|
|
| prop:vtxr:582 |
Sensitivity |
not BCR::ABL1
|
Acute Lymphoid Leukemia |
Ponatinib
|
|
| prop:vtxr:583 |
Sensitivity |
ABL1 p.T315I, not BCR::ABL1
|
Acute Lymphoid Leukemia |
Ponatinib
|
|
| prop:vtxr:584 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Durvalumab
|
|
| prop:vtxr:585 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Durvalumab,
Tremelimumab
|
|
| prop:vtxr:586 |
Sensitivity |
pMMR
|
Endometrial Carcinoma |
Carboplatin,
Durvalumab,
Olaparib,
Paclitaxel
|
|
| prop:vtxr:587 |
Sensitivity |
MSI-H
|
Endometrial Carcinoma |
Dostarlimab
|
|
| prop:vtxr:588 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Pembrolizumab
|
|
| prop:vtxr:589 |
Sensitivity |
CD274 amplification, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Pembrolizumab
|
|
| prop:vtxr:592 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Gemcitabine,
Pembrolizumab
|
|
| prop:vtxr:593 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Gemcitabine,
Pembrolizumab
|
|
| prop:vtxr:594 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:595 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Bladder Urothelial Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:596 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Head and Neck Squamous Cell Carcinoma |
Carboplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:597 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Head and Neck Squamous Cell Carcinoma |
Cisplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:598 |
Sensitivity |
PD-L1 >= 50%
|
Head and Neck Squamous Cell Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:599 |
Sensitivity |
dMMR
|
Endometrial Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:600 |
Sensitivity |
MSI-H
|
Esophagogastric Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:601 |
Sensitivity |
dMMR
|
Esophagogastric Adenocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:602 |
Sensitivity |
MSI-H
|
Gastrointestinal Stromal Tumor |
Pembrolizumab
|
|
| prop:vtxr:603 |
Sensitivity |
dMMR
|
Gastrointestinal Stromal Tumor |
Pembrolizumab
|
|
| prop:vtxr:604 |
Sensitivity |
MSI-H
|
Cholangiocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:605 |
Sensitivity |
dMMR
|
Cholangiocarcinoma |
Pembrolizumab
|
|
| prop:vtxr:606 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Esophageal Adenocarcinoma |
Cisplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:607 |
Sensitivity |
PD-L1 (CPS) >= 10
|
Esophageal Adenocarcinoma |
Carboplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:608 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Pembrolizumab
|
|
| prop:vtxr:609 |
Sensitivity |
ER negative, HER2-negative, PD-L1 (CPS) >= 10, PR negative
|
Invasive Breast Carcinoma |
Nab-paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:610 |
Sensitivity |
HER2-positive, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Carboplatin,
Fluorouracil,
Pembrolizumab,
Trastuzumab
|
|
| prop:vtxr:611 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:612 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Carboplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:613 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Trastuzumab emtansine
|
|
| prop:vtxr:618 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR, Wild type ROS1
|
Non-Small Cell Lung Cancer |
Cemiplimab
|
|
| prop:vtxr:619 |
Sensitivity |
PD-L1 >= 1%, Wild type ALK, Wild type EGFR, Wild type ROS1
|
Non-Small Cell Lung Cancer |
Carboplatin,
Cemiplimab,
Pemetrexed
|
|
| prop:vtxr:620 |
Sensitivity |
pMMR
|
Endometrial Carcinoma |
Durvalumab,
Olaparib
|
|
| prop:vtxr:621 |
Sensitivity |
FGFR2 rearrangements
|
Cholangiocarcinoma |
Futibatinib
|
|
| prop:vtxr:622 |
Sensitivity |
CD20 +
|
Diffuse Large B-Cell Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:624 |
Sensitivity |
CD20 +
|
Diffuse Large B-Cell Lymphoma |
Corticosteroid,
Cyclophosphamide,
Cytarabine,
Doxorubicin,
Etoposide,
Methotrexate,
Rituximab,
Vincristine
|
|
| prop:vtxr:625 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Corticosteroid,
Cyclophosphamide,
Cytarabine,
Doxorubicin,
Etoposide,
Methotrexate,
Rituximab,
Vincristine
|
|
| prop:vtxr:626 |
Sensitivity |
CD20 +
|
Burkitt Lymphoma |
Corticosteroid,
Cyclophosphamide,
Cytarabine,
Doxorubicin,
Etoposide,
Methotrexate,
Rituximab,
Vincristine
|
|
| prop:vtxr:627 |
Sensitivity |
BRAF p.V600K
|
Non-Small Cell Lung Cancer |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:628 |
Sensitivity |
CD33 +
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Gemtuzumab ozogamicin
|
|
| prop:vtxr:629 |
Sensitivity |
ER positive, HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:630 |
Sensitivity |
ER positive, HER2-positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:631 |
Sensitivity |
HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:632 |
Sensitivity |
ER positive, ERBB2 amplification, PR positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:633 |
Sensitivity |
ER positive, ERBB2 amplification
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:634 |
Sensitivity |
ERBB2 amplification, PR positive
|
Invasive Breast Carcinoma |
Neratinib
|
|
| prop:vtxr:638 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Carboplatin,
Nivolumab,
Paclitaxel
|
|
| prop:vtxr:639 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Carboplatin,
Nivolumab,
Pemetrexed
|
|
| prop:vtxr:640 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Cisplatin,
Gemcitabine,
Nivolumab
|
|
| prop:vtxr:641 |
Sensitivity |
PD-L1 >= 1%
|
Bladder Urothelial Carcinoma |
Nivolumab
|
|
| prop:vtxr:642 |
Sensitivity |
PD-L1 >= 1%
|
Esophageal Squamous Cell Carcinoma |
Ipilimumab,
Nivolumab
|
|
| prop:vtxr:643 |
Sensitivity |
PD-L1 >= 1%
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Fluorouracil,
Nivolumab
|
|
| prop:vtxr:644 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Esophageal Adenocarcinoma |
Fluorouracil,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:645 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Esophageal Adenocarcinoma |
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:646 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Esophagogastric Adenocarcinoma |
Fluorouracil,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:647 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Esophagogastric Adenocarcinoma |
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:648 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Adenocarcinoma of the Gastroesophageal Junction |
Fluorouracil,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:649 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Adenocarcinoma of the Gastroesophageal Junction |
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:650 |
Sensitivity |
PD-L1 < 1%
|
Melanoma |
Nivolumab,
Relatlimab
|
|
| prop:vtxr:651 |
Sensitivity |
FGFR2::v
|
Cholangiocarcinoma |
Elacestrant
|
|
| prop:vtxr:652 |
Sensitivity |
FGFR2 rearrangements
|
Cholangiocarcinoma |
Elacestrant
|
|
| prop:vtxr:653 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:654 |
Sensitivity |
HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:655 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants, PR positive
|
Invasive Breast Carcinoma |
Alpelisib,
Fulvestrant
|
|
| prop:vtxr:656 |
Sensitivity |
v::RET
|
Papillary Thyroid Cancer |
Selpercatinib
|
|
| prop:vtxr:657 |
Sensitivity |
RET p.M918T
|
Medullary Thyroid Cancer |
Selpercatinib
|
|
| prop:vtxr:658 |
Sensitivity |
5q deletion
|
Myeloproliferative Neoplasm |
Lenalidomide
|
|
| prop:vtxr:659 |
Sensitivity |
not BCR::ABL1
|
Chronic Myelogenous Leukemia |
Asciminib
|
|
| prop:vtxr:660 |
Sensitivity |
BRAF p.V600E
|
High-Grade Glioma, NOS |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:661 |
Sensitivity |
not BCR::ABL1
|
Chronic Myelogenous Leukemia |
Dasatinib
|
|
| prop:vtxr:662 |
Sensitivity |
not BCR::ABL1
|
Acute Lymphoid Leukemia |
Dasatinib
|
|
| prop:vtxr:663 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Dabrafenib
|
|
| prop:vtxr:664 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Osimertinib
|
|
| prop:vtxr:665 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Cisplatin,
Osimertinib
|
|
| prop:vtxr:666 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Carboplatin,
Osimertinib
|
|
| prop:vtxr:667 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Cisplatin,
Osimertinib
|
|
| prop:vtxr:668 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Carboplatin,
Osimertinib
|
|
| prop:vtxr:669 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Erlotinib
|
|
| prop:vtxr:670 |
Sensitivity |
not BCR::ABL1
|
Chronic Myelogenous Leukemia |
Nilotinib
|
|
| prop:vtxr:671 |
Sensitivity |
PD-L1 >= 5%
|
Bladder Urothelial Carcinoma |
Atezolizumab
|
|
| prop:vtxr:672 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:673 |
Sensitivity |
EGFR Somatic variants
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Bevacizumab,
Carboplatin,
Paclitaxel
|
|
| prop:vtxr:674 |
Sensitivity |
v::ALK
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Bevacizumab,
Carboplatin,
Paclitaxel
|
|
| prop:vtxr:675 |
Sensitivity |
Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Carboplatin,
Nab-paclitaxel
|
|
| prop:vtxr:676 |
Sensitivity |
Wild type ALK
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Carboplatin,
Nab-paclitaxel
|
|
| prop:vtxr:677 |
Sensitivity |
Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab,
Carboplatin,
Nab-paclitaxel
|
|
| prop:vtxr:678 |
Sensitivity |
PD-L1 >= 10% TIIC, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Atezolizumab
|
|
| prop:vtxr:679 |
Sensitivity |
ER negative, HER2-negative, PD-L1 >= 1%, PR negative
|
Invasive Breast Carcinoma |
Atezolizumab,
Nab-paclitaxel
|
|
| prop:vtxr:685 |
Sensitivity |
ER positive, HER2-positive, PR negative
|
Invasive Breast Carcinoma |
Lapatinib,
Trastuzumab
|
|
| prop:vtxr:687 |
Sensitivity |
ERBB2 amplification
|
Invasive Breast Carcinoma |
Capecitabine,
Lapatinib
|
|
| prop:vtxr:688 |
Sensitivity |
ER positive, ERBB2 amplification, PR negative
|
Invasive Breast Carcinoma |
Lapatinib,
Trastuzumab
|
|
| prop:vtxr:689 |
Sensitivity |
ER positive, ERBB2 amplification, PR positive
|
Invasive Breast Carcinoma |
Lapatinib,
Letrozole
|
|
| prop:vtxr:690 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Fluorouracil,
Oxaliplatin,
Panitumumab
|
|
| prop:vtxr:691 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Fluorouracil,
Irinotecan,
Panitumumab
|
|
| prop:vtxr:692 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Panitumumab
|
|
| prop:vtxr:693 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Venetoclax
|
|
| prop:vtxr:694 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Venetoclax
|
|
| prop:vtxr:695 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Venetoclax
|
|
| prop:vtxr:696 |
Sensitivity |
Wild type TP53
|
Chronic Lymphocytic Leukemia |
Venetoclax
|
|
| prop:vtxr:708 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Dacomitinib
|
|
| prop:vtxr:711 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Vemurafenib
|
|
| prop:vtxr:712 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Rituximab
|
|
| prop:vtxr:713 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Rituximab
|
|
| prop:vtxr:714 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Rituximab
|
|
| prop:vtxr:715 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Carboplatin,
Pemetrexed,
Tislelizumab
|
|
| prop:vtxr:716 |
Sensitivity |
PD-L1 >= 50%, Wild type ALK, Wild type EGFR
|
Non-Small Cell Lung Cancer |
Cisplatin,
Pemetrexed,
Tislelizumab
|
|
| prop:vtxr:717 |
Sensitivity |
ER positive, HER2-negative, PIK3CA Somatic variants
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:718 |
Sensitivity |
ER positive, HER2-negative, PIK3CA amplification
|
Invasive Breast Carcinoma |
Capivasertib,
Fulvestrant
|
|
| prop:vtxr:719 |
Sensitivity |
FGFR2::BICC1
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:720 |
Sensitivity |
FGFR2::CASP7
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:721 |
Sensitivity |
FGFR3::BAIAP2L1
|
Bladder Urothelial Carcinoma |
Erdafitinib
|
|
| prop:vtxr:741 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Zanubrutinib
|
|
| prop:vtxr:742 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Zanubrutinib
|
|
| prop:vtxr:743 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Zanubrutinib
|
|
| prop:vtxr:744 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Acalabrutinib
|
|
| prop:vtxr:745 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Acalabrutinib
|
|
| prop:vtxr:746 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Acalabrutinib
|
|
| prop:vtxr:747 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Ibrutinib
|
|
| prop:vtxr:748 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Ibrutinib
|
|
| prop:vtxr:749 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Ibrutinib
|
|
| prop:vtxr:757 |
Sensitivity |
CD30 +
|
Hodgkin Lymphoma |
Brentuximab vedotin,
Cisplatin,
Cytarabine,
Etoposide
|
|
| prop:vtxr:758 |
Sensitivity |
CD33 +
|
Acute Lymphoid Leukemia |
Cytarabine,
Daunorubicin,
Gemtuzumab ozogamicin
|
|
| prop:vtxr:759 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Carboplatin,
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:760 |
Sensitivity |
CD30 +, HER2-negative
|
Hodgkin Lymphoma |
Brentuximab vedotin,
Carboplatin,
Etoposide,
Ifosfamide
|
|
| prop:vtxr:761 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 10
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Pembrolizumab
|
|
| prop:vtxr:762 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 10
|
Adenocarcinoma of the Gastroesophageal Junction |
Fluorouracil,
Oxaliplatin,
Pembrolizumab
|
|
| prop:vtxr:763 |
Sensitivity |
not BCR::ABL1
|
Acute Lymphoid Leukemia |
Blinatumomab
|
|
| prop:vtxr:764 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Paclitaxel,
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:765 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Pertuzumab,
Trastuzumab,
Vinorelbine
|
|
| prop:vtxr:766 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Pertuzumab,
Trastuzumab
|
|
| prop:vtxr:767 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Carboplatin,
Gemcitabine,
Nivolumab
|
|
| prop:vtxr:768 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Cisplatin,
Nivolumab,
Pemetrexed
|
|
| prop:vtxr:769 |
Sensitivity |
HER2-negative
|
Invasive Breast Carcinoma |
Bevacizumab,
Paclitaxel
|
|
| prop:vtxr:770 |
Sensitivity |
EGFR activating variants
|
Non-Small Cell Lung Cancer |
Bevacizumab,
Erlotinib
|
|
| prop:vtxr:771 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Capecitabine
|
|
| prop:vtxr:772 |
Sensitivity |
ER positive
|
Invasive Breast Carcinoma |
Tamoxifen
|
|
| prop:vtxr:773 |
Sensitivity |
ER positive, HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:774 |
Sensitivity |
ER positive, HER2-positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:775 |
Sensitivity |
HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:776 |
Sensitivity |
ER positive, ERBB2 amplification, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:777 |
Sensitivity |
ER positive, ERBB2 amplification
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:778 |
Sensitivity |
ERBB2 amplification, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:782 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Carboplatin,
Cyclophosphamide,
Doxorubicin,
Paclitaxel
|
|
| prop:vtxr:783 |
Sensitivity |
ER negative
|
Invasive Breast Carcinoma |
Fulvestrant
|
|
| prop:vtxr:784 |
Sensitivity |
ER positive, PR positive
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:785 |
Sensitivity |
ER positive
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:786 |
Sensitivity |
PR positive
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:787 |
Sensitivity |
ER positive, PR positive
|
Invasive Breast Carcinoma |
Exemestane
|
|
| prop:vtxr:788 |
Sensitivity |
ER positive
|
Invasive Breast Carcinoma |
Exemestane
|
|
| prop:vtxr:789 |
Sensitivity |
PR positive
|
Invasive Breast Carcinoma |
Exemestane
|
|
| prop:vtxr:790 |
Sensitivity |
ER negative, HER2-negative, PR negative
|
Invasive Breast Carcinoma |
Carboplatin,
Gemcitabine
|
|
| prop:vtxr:791 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Cyclophosphamide,
Doxorubicin,
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:792 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Exemestane
|
|
| prop:vtxr:793 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Exemestane
|
|
| prop:vtxr:794 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Abemaciclib,
Exemestane
|
|
| prop:vtxr:796 |
Sensitivity |
EGFR positive, Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab
|
|
| prop:vtxr:797 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Fluorouracil,
Irinotecan
|
|
| prop:vtxr:798 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Cetuximab,
Irinotecan
|
|
| prop:vtxr:800 |
Sensitivity |
PD-L1 >= 1%
|
Esophageal Squamous Cell Carcinoma |
Fluorouracil,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:801 |
Sensitivity |
TP53 Somatic variants
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Ofatumumab
|
|
| prop:vtxr:802 |
Sensitivity |
TP53 deletion
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Ofatumumab
|
|
| prop:vtxr:803 |
Sensitivity |
not 17p deletion
|
Chronic Lymphocytic Leukemia |
Idelalisib,
Ofatumumab
|
|
| prop:vtxr:804 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Midostaurin
|
|
| prop:vtxr:808 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Bendamustine,
Rituximab
|
|
| prop:vtxr:809 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cisplatin,
Cytarabine,
Rituximab
|
|
| prop:vtxr:810 |
Sensitivity |
CD20 +
|
Diffuse Large B-Cell Lymphoma |
Cyclophosphamide,
Doxorubicin,
Etoposide,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:811 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Doxorubicin,
Etoposide,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:812 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Carboplatin,
Etoposide,
Ifosfamide,
Rituximab
|
|
| prop:vtxr:813 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisolone,
Rituximab,
Vinorelbine
|
|
| prop:vtxr:814 |
Sensitivity |
CD20 +
|
Diffuse Large B-Cell Lymphoma |
Gemcitabine,
Oxaliplatin,
Rituximab
|
|
| prop:vtxr:815 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Gemcitabine,
Oxaliplatin,
Rituximab
|
|
| prop:vtxr:816 |
Sensitivity |
CD20 +
|
Non-Hodgkin Lymphoma |
Cyclophosphamide,
Etoposide,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:817 |
Sensitivity |
CD30 +
|
Hodgkin Lymphoma |
Bendamustine,
Brentuximab vedotin
|
|
| prop:vtxr:818 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Cyclophosphamide,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:819 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Cyclophosphamide,
Doxorubicin,
Prednisolone,
Rituximab,
Vincristine
|
|
| prop:vtxr:820 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Chlorambucil,
Mitoxantrone,
Prednisolone,
Rituximab
|
|
| prop:vtxr:821 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Cyclophosphamide,
Doxorubicin,
Etoposide,
Interferon Alpha,
Prednisolone,
Rituximab
|
|
| prop:vtxr:822 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Rituximab
|
|
| prop:vtxr:824 |
Sensitivity |
ER positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:825 |
Sensitivity |
PR positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:826 |
Sensitivity |
ER positive, PR positive
|
Invasive Breast Carcinoma |
Anastrozole
|
|
| prop:vtxr:827 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:828 |
Sensitivity |
HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:829 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Letrozole
|
|
| prop:vtxr:836 |
Sensitivity |
v::ROS1
|
Non-Small Cell Lung Cancer |
Taletrectinib
|
|
| prop:vtxr:837 |
Sensitivity |
c-Met >= 50%
|
Lung Non-Squamous Non-Small Cell Carcinoma |
Telisotuzumab Vedotin
|
|
| prop:vtxr:838 |
Sensitivity |
KRAS p.G12C
|
Low-Grade Serous Ovarian Cancer |
Avutometinib,
Defactinib
|
|
| prop:vtxr:839 |
Sensitivity |
KRAS p.G12V
|
Low-Grade Serous Ovarian Cancer |
Avutometinib,
Defactinib
|
|
| prop:vtxr:840 |
Sensitivity |
t(15;17)
|
APL with PML-RARA |
Arsenic trioxide
|
|
| prop:vtxr:841 |
Sensitivity |
CD30 +
|
Mycosis Fungoides |
Brentuximab vedotin,
Cyclophosphamide,
Doxorubicin,
Prednisone
|
|
| prop:vtxr:842 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Docetaxel,
Paclitaxel,
Trastuzumab
|
|
| prop:vtxr:843 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Pembrolizumab
|
|
| prop:vtxr:844 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Pembrolizumab
|
|
| prop:vtxr:845 |
Sensitivity |
BRAF p.V600E
|
Melanoma |
Nivolumab
|
|
| prop:vtxr:846 |
Sensitivity |
BRAF p.V600K
|
Melanoma |
Nivolumab
|
|
| prop:vtxr:847 |
Sensitivity |
CD30 +
|
Angioimmunoblastic T-Cell Lymphoma |
Brentuximab vedotin,
Cyclophosphamide,
Doxorubicin,
Prednisone
|
|
| prop:vtxr:848 |
Sensitivity |
CD30 +
|
Peripheral T-Cell lymphoma, NOS |
Brentuximab vedotin,
Cyclophosphamide,
Doxorubicin,
Prednisone
|
|
| prop:vtxr:849 |
Sensitivity |
EGFR Somatic variants
|
Non-Small Cell Lung Cancer |
Datopotamab deruxtecan
|
|
| prop:vtxr:850 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Datopotamab deruxtecan
|
|
| prop:vtxr:851 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Datopotamab deruxtecan
|
|
| prop:vtxr:852 |
Sensitivity |
EGFR p.T790M
|
Non-Small Cell Lung Cancer |
Datopotamab deruxtecan
|
|
| prop:vtxr:853 |
Sensitivity |
EGFR Exon 20 (Insertion)
|
Invasive Breast Carcinoma |
Datopotamab deruxtecan
|
|
| prop:vtxr:854 |
Sensitivity |
ER positive, HER2-negative
|
Invasive Breast Carcinoma |
Datopotamab deruxtecan
|
|
| prop:vtxr:855 |
Sensitivity |
HER2-negative, PR positive
|
Non-Small Cell Lung Cancer |
Datopotamab deruxtecan
|
|
| prop:vtxr:856 |
Sensitivity |
ER positive, HER2-negative, PR positive
|
Invasive Breast Carcinoma |
Datopotamab deruxtecan
|
|
| prop:vtxr:857 |
Sensitivity |
EGFR Exon 20 (Insertion)
|
Non-Small Cell Lung Cancer |
Sunvozertinib
|
|
| prop:vtxr:858 |
Sensitivity |
ERBB2 TKD activating variants
|
Lung Non-Squamous Non-Small Cell Carcinoma |
Zongertinib
|
|
| prop:vtxr:859 |
Sensitivity |
ER positive, HER2-low
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:860 |
Sensitivity |
HER2-low, PR positive
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:861 |
Sensitivity |
ER positive, HER2-low, PR positive
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:862 |
Sensitivity |
ER positive, HER2-ultralow
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:863 |
Sensitivity |
HER2-ultralow, PR positive
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:864 |
Sensitivity |
ER positive, HER2-ultralow, PR positive
|
Invasive Breast Carcinoma |
Trastuzumab deruxtecan
|
|
| prop:vtxr:865 |
Sensitivity |
PD-L1 >= 1%
|
Non-Small Cell Lung Cancer |
Cisplatin,
Docetaxel,
Nivolumab
|
|
| prop:vtxr:866 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:867 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Cisplatin,
Tislelizumab
|
|
| prop:vtxr:868 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Fluorouracil,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:869 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:870 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:871 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Esophageal Squamous Cell Carcinoma |
Oxaliplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:872 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:873 |
Sensitivity |
PD-L1 (TAP) >= 5%
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:874 |
Sensitivity |
H3-3A p.K28M
|
Diffuse Midline Glioma |
Dordaviprone
|
|
| prop:vtxr:875 |
Sensitivity |
ER positive, ESR1 activating variants, HER2-negative
|
Invasive Breast Carcinoma |
Imlunestrant
|
|
| prop:vtxr:876 |
Sensitivity |
HER2-positive, Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Trastuzumab,
Tucatinib
|
|
| prop:vtxr:877 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Quizartinib
|
|
| prop:vtxr:878 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Cytarabine,
Daunorubicin,
Quizartinib
|
|
| prop:vtxr:879 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Cytarabine,
Idarubicin,
Quizartinib
|
|
| prop:vtxr:880 |
Sensitivity |
NPM1 p.W288Cfs*12
|
Acute Myeloid Leukemia |
Ziftomenib
|
|
| prop:vtxr:881 |
Sensitivity |
ERBB2 TKD activating variants
|
Lung Non-Squamous Non-Small Cell Carcinoma |
Sevabertinib
|
|
| prop:vtxr:882 |
Sensitivity |
HER2-positive
|
Invasive Breast Carcinoma |
Pertuzumab,
Trastuzumab deruxtecan
|
|
| prop:vtxr:883 |
Sensitivity |
NPM1 p.W288Cfs*12
|
Acute Myeloid Leukemia |
Revumenib
|
|
| prop:vtxr:884 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:885 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Cisplatin,
Tislelizumab
|
|
| prop:vtxr:886 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Fluorouracil,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:887 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:888 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:889 |
Sensitivity |
PD-L1 (TAP) >= 1%
|
Esophageal Squamous Cell Carcinoma |
Oxaliplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:890 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:891 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Cisplatin,
Tislelizumab
|
|
| prop:vtxr:892 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Fluorouracil,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:893 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:894 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Cisplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:895 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Esophageal Squamous Cell Carcinoma |
Oxaliplatin,
Paclitaxel,
Tislelizumab
|
|
| prop:vtxr:896 |
Sensitivity |
HER2-negative, PD-L1 (TAP) >= 1%
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:897 |
Sensitivity |
HER2-negative, PD-L1 (TAP) >= 1%
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:898 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Oxaliplatin,
Tislelizumab
|
|
| prop:vtxr:899 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 1
|
Adenocarcinoma of the Gastroesophageal Junction |
Cisplatin,
Fluorouracil,
Tislelizumab
|
|
| prop:vtxr:900 |
Sensitivity |
NPM1 p.W288Cfs*12
|
Acute Lymphoid Leukemia |
Revumenib
|
|
| prop:vtxr:901 |
Sensitivity |
NPM1 p.W288Cfs*12
|
Burkitt Lymphoma |
Revumenib
|
|
| prop:vtxr:902 |
Sensitivity |
NPM1 p.W288Cfs*12
|
Acute Leukemias of Ambiguous Lineage |
Revumenib
|
|
| prop:vtxr:903 |
Sensitivity |
FGFR2::v
|
Cholangiocarcinoma |
Futibatinib
|
|
| prop:vtxr:904 |
Sensitivity |
BRAF p.V600E
|
Colorectal Adenocarcinoma |
Cetuximab,
Encorafenib,
Fluorouracil,
Irinotecan
|
|
| prop:vtxr:905 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Ovarian Epithelial Tumor |
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:906 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Ovarian Epithelial Tumor |
Bevacizumab,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:907 |
Sensitivity |
PD-L1 (CPS) >= 1
|
High-Grade Serous Fallopian Tube Cancer |
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:908 |
Sensitivity |
PD-L1 (CPS) >= 1
|
High-Grade Serous Fallopian Tube Cancer |
Bevacizumab,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:909 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Peritoneal Serous Carcinoma |
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:910 |
Sensitivity |
PD-L1 (CPS) >= 1
|
Peritoneal Serous Carcinoma |
Bevacizumab,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:911 |
Sensitivity |
EGFR TKD activating variants
|
Non-Small Cell Lung Cancer |
Gefitinib
|
|
| prop:vtxr:912 |
Sensitivity |
VHL pathogenic variants
|
Renal Cell Carcinoma |
Belzutifan
|
|
| prop:vtxr:913 |
Sensitivity |
VHL pathogenic variants
|
Central Nervous System Hemangioblastoma |
Belzutifan
|
|
| prop:vtxr:914 |
Sensitivity |
VHL pathogenic variants
|
Pancreatic Neuroendocrine Tumor |
Belzutifan
|
|
| prop:vtxr:915 |
Sensitivity |
Wild type KRAS, Wild type NRAS
|
Colorectal Adenocarcinoma |
Fruquintinib
|
|
| prop:vtxr:916 |
Sensitivity |
PD-L1 > 0%
|
Non-Small Cell Lung Cancer |
Nivolumab
|
|
| prop:vtxr:917 |
Sensitivity |
PD-L1 > 0%
|
Non-Small Cell Lung Cancer |
Carboplatin,
Paclitaxel,
Pembrolizumab
|
|
| prop:vtxr:918 |
Sensitivity |
HLA-A*02:01
|
Uveal Melanoma |
Tebentafusp
|
|
| prop:vtxr:919 |
Sensitivity |
CD30 +
|
Hodgkin Lymphoma |
Brentuximab vedotin,
Cyclophosphamide,
Dacarbazine,
Dexamethasone,
Doxorubicin,
Etoposide
|
|
| prop:vtxr:920 |
Sensitivity |
BRAF p.V600E
|
Differentiated Thyroid Gland Carcinoma |
Dabrafenib,
Trametinib
|
|
| prop:vtxr:921 |
Sensitivity |
EGFR Exon 19 (Deletion)
|
Non-Small Cell Lung Cancer |
Aumolertinib
|
|
| prop:vtxr:922 |
Sensitivity |
EGFR p.L858R
|
Non-Small Cell Lung Cancer |
Aumolertinib
|
|
| prop:vtxr:923 |
Sensitivity |
EGFR p.T790M
|
Non-Small Cell Lung Cancer |
Aumolertinib
|
|
| prop:vtxr:924 |
Sensitivity |
ER positive, ESR1 activating variants, HER2-negative
|
Invasive Breast Carcinoma |
Abemaciclib,
Camizestrant
|
|
| prop:vtxr:925 |
Sensitivity |
ER positive, ESR1 activating variants, HER2-negative
|
Invasive Breast Carcinoma |
Camizestrant,
Palbociclib
|
|
| prop:vtxr:926 |
Sensitivity |
ER positive, ESR1 activating variants, HER2-negative
|
Invasive Breast Carcinoma |
Camizestrant,
Ribociclib
|
|
| prop:vtxr:927 |
Sensitivity |
t(11;14)
|
Mantle Cell Lymphoma |
Ibrutinib
|
|
| prop:vtxr:928 |
Sensitivity |
CCND1
|
Mantle Cell Lymphoma |
Ibrutinib
|
|
| prop:vtxr:929 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Bendamustine,
Obinutuzumab
|
|
| prop:vtxr:930 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Cyclophosphamide,
Doxorubicin,
Obinutuzumab,
Prednisolone,
Vincristine
|
|
| prop:vtxr:931 |
Sensitivity |
CD20 +
|
Follicular Lymphoma |
Cyclophosphamide,
Obinutuzumab,
Prednisolone,
Vincristine
|
|
| prop:vtxr:932 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Stomach Adenocarcinoma |
Capecitabine,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:933 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Adenocarcinoma of the Gastroesophageal Junction |
Capecitabine,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:934 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Esophageal Adenocarcinoma |
Capecitabine,
Nivolumab,
Oxaliplatin
|
|
| prop:vtxr:935 |
Sensitivity |
BCR::ABL1
|
Acute Lymphoid Leukemia |
Daunorubicin,
Dexamethasone,
Imatinib,
Methotrexate,
Vincristine
|
|
| prop:vtxr:936 |
Sensitivity |
BCR::ABL1, CD20 +
|
Acute Lymphoid Leukemia |
Daunorubicin,
Dexamethasone,
Imatinib,
Methotrexate,
Rituximab,
Vincristine
|
|
| prop:vtxr:937 |
Sensitivity |
CD20 +
|
Acute Lymphoid Leukemia |
Daunorubicin,
Dexamethasone,
Methotrexate,
Rituximab,
Vincristine
|
|
| prop:vtxr:938 |
Sensitivity |
FLT3-ITD
|
Acute Myeloid Leukemia |
Cytarabine,
Quizartinib
|
|
| prop:vtxr:939 |
Sensitivity |
HER2-positive, PR positive
|
Invasive Breast Carcinoma |
Anastrozole,
Trastuzumab
|
|
| prop:vtxr:940 |
Sensitivity |
HER2-negative, PD-L1 (CPS) >= 5
|
Stomach Adenocarcinoma |
Fluorouracil,
Nivolumab,
Oxaliplatin
|
|