KRAS p.G12C

About

Biomarker type: Somatic variant

Gene context: KRAS

HGVS.p: NP_004976.2:p.Gly12Cys

Mappings

Therapeutic response

Precision oncology relationships for therapeutic response involving this biomarker.

Organizations Biomarkers Cancer types Therapies
FDA (1) KRAS p.G12C Non-Small Cell Lung Cancer Adagrasib
FDA (1) HC (1) KRAS p.G12C Non-Small Cell Lung Cancer Sotorasib
FDA (1) KRAS p.G12C Colorectal Adenocarcinoma Adagrasib, Cetuximab
FDA (1) KRAS p.G12C Low-Grade Serous Ovarian Cancer Avutometinib, Defactinib