EGFR p.L858R

About

Biomarker type: Somatic variant

Gene context: EGFR

HGVS.p: NP_005219.2:p.Leu858Arg

Mappings

Therapeutic response

Precision oncology relationships for therapeutic response involving this biomarker.

Organizations Biomarkers Cancer types Therapies
FDA (1) EGFR p.L858R Non-Small Cell Lung Cancer Dacomitinib
FDA (1) EGFR p.L858R Non-Small Cell Lung Cancer Erlotinib
FDA (1) HC (1) EGFR p.L858R Non-Small Cell Lung Cancer Gefitinib
FDA (3) HC (3) EGFR p.L858R Non-Small Cell Lung Cancer Osimertinib
FDA (1) HC (1) EGFR p.L858R Non-Small Cell Lung Cancer Cisplatin, Osimertinib, Pemetrexed
FDA (1) HC (1) EGFR p.L858R Non-Small Cell Lung Cancer Carboplatin, Osimertinib, Pemetrexed
FDA (1) EGFR p.L858R Non-Small Cell Lung Cancer Erlotinib, Ramucirumab
FDA (2) HC (1) EGFR p.L858R Non-Small Cell Lung Cancer Amivantamab, Lazertinib
FDA (1) HC (1) EGFR p.L858R Non-Small Cell Lung Cancer Amivantamab, Carboplatin, Pemetrexed
FDA (1) EGFR p.L858R Non-Small Cell Lung Cancer Datopotamab deruxtecan