ESR1
About
Location: 6q25.1-q25.2
Mappings
Biomarkers
ESR1 is involved in the following curated biomarkers.
| Name | Biomarker type | Propositions | Statements |
|---|---|---|---|
| ESR1 activating variants | Somatic variant | 3 | 3 |
Therapeutic response
Precision oncology relationships for therapeutic response involving this gene.
Organizations
Biomarkers
Cancer types
Therapies
| Organizations | Biomarkers | Cancer types | Therapies | |
|---|---|---|---|---|
| FDA (2) | ER positive, ESR1 activating variants, HER2-negative | Invasive Breast Carcinoma | Elacestrant | |
| FDA (2) | ER positive, ESR1 activating variants, HER2-negative | Invasive Breast Carcinoma | Imlunestrant | |
| FDA (2) | ER positive, ESR1 activating variants, HER2-negative | Invasive Breast Carcinoma | Vepdegestrant |