ESR1

About

Location: 6q25.1-q25.2

Mappings

HGNC: HGNC:3467

Ensembl: ENSG00000091831

NCBI: 2099

Refseq: NM_000125.4

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Biomarkers

ESR1 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
ESR1 activating variants Somatic variant 2 2

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organizations Biomarkers Cancer types Therapies
FDA (1) ER positive, ESR1 activating variants, HER2-negative Invasive Breast Carcinoma Elacestrant
FDA (1) ER positive, ESR1 activating variants, HER2-negative Invasive Breast Carcinoma Imlunestrant